Effect of usnic acid on Candida orthopsilosis and C. parapsilosis.

نویسندگان

  • Regina Helena Pires
  • Rodrigo Lucarini
  • Maria Jose Soares Mendes-Giannini
چکیده

The activity of usnic acid against Candida orthopsilosis and Candida parapsilosis on planktonic and biofilm conditions was investigated by using a broth microdilution and microplate methods. Potent in vitro activities against different Candida species were obtained. The metabolic activity of sessile cells of C. parapsilosis complex was reduced by 80% at four times the 80% inhibitory concentration. The in vitro studies support further efforts to determine whether usnic acid can be used clinically to cure patients with Candida infections.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 56 1  شماره 

صفحات  -

تاریخ انتشار 2012